The couple spoke candidly about their relationship during an appearance on Neha Dhupia and Angad Bedi’s chat show Double Date, marking the first time they publicly discussed rumours of separation and divorce that had circulated over the past several months.

The speculation had intensified after Prince and Yuvika unfollowed each other on Instagram. Earlier, comments made by Prince in a vlog had also triggered reports suggesting the couple were living separately and heading towards a split.

Clarifying the controversy, Prince said his statement in the vlog had been taken out of context. According to him, the period coincided with several major developments in their lives, including Yuvika’s pregnancy, the construction of their new home and growing work commitments.

Prince explained that he wanted their child to arrive in a fully completed home. Since the house was still under construction and filled with dust, which could affect Yuvika’s health, she temporarily stayed at her mother’s residence. During the vlog, he mentioned that they were not living together, referring only to the fact that they were staying in different locations for practical reasons.

However, the remark quickly led to assumptions that the marriage was in trouble.

While dismissing the divorce rumours, Prince admitted that the relationship had gone through a difficult phase. He said there was a time when both of them were emotionally exhausted and struggled to cope with the pressures surrounding them.

According to Prince, neither he nor Yuvika was at fault during that period. Instead, both were dealing with circumstances that affected their mental well-being and decision-making. He acknowledged that separation had crossed their minds but said they eventually worked through the challenges and chose to stay together.

The conversation also touched on the emotional impact of parenthood. Yuvika became visibly emotional while discussing her experience after giving birth to the couple’s daughter in 2024.

She revealed that the months following delivery were physically and mentally demanding. Changes in her body and the challenges of adjusting to motherhood affected her confidence. At the same time, she was dealing with postpartum struggles while also supporting Prince through episodes of anxiety.

Yuvika said she tried to remain strong for the sake of their daughter and focused on ensuring that family tensions did not affect the child. The actress described the transition into parenthood as a life-changing experience filled with responsibility, emotional ups and downs and constant adjustment.

The couple also addressed the recent social media activity that reignited rumours about their relationship. When fans noticed that they had unfollowed each other on Instagram, speculation quickly spread across entertainment portals and social media platforms.

Prince and Yuvika said they were initially bothered by the assumptions being made about their personal lives. Over time, however, they decided that not every rumour required a public response and chose to focus on their family instead.

Prince Narula and Yuvika Chaudhary first met in 2015 during their stint on the reality show Bigg Boss 9. What began as a friendship inside the house gradually turned into a relationship. The couple tied the knot in 2018 and became one of television’s most popular celebrity pairs.

Six years after their marriage, they welcomed their daughter through IVF in 2024. Their latest comments offer a rare glimpse into the challenges they faced behind the scenes while navigating marriage, parenthood and public scrutiny.

A major breakthrough in human gene-editing research has brought the possibility of preventing inherited diseases a step closer to reality. Scientists at Columbia University have successfully edited the DNA of early-stage human embryos with an accuracy level not previously achieved. While researchers say the technology could one day help eliminate certain genetic disorders, the development has also reignited global ethical concerns about the future creation of so-called “designer babies.”

The study was led by geneticist Dieter Egli and focused on a newer gene-editing technique known as base editing. Unlike traditional CRISPR technology, which cuts DNA strands, base editing makes highly targeted changes to individual genetic letters. Researchers say this approach significantly reduces the risk of unintended genetic damage, a major challenge that has limited embryo-editing research in the past.

According to the research team, the technology is still experimental and not ready for clinical use. However, the findings mark an important step toward understanding whether inherited diseases could one day be corrected before birth.

More Precise Than Earlier Methods

The researchers targeted two genes during the experiment. One of them, PCSK9, is associated with cholesterol levels and the risk of heart disease, while the HBG gene plays a role in the production of fetal haemoglobin.

Using donated fertilised eggs and two-cell embryos, scientists introduced base-editing molecules and successfully modified both genes. In several cases, they were able to edit both targets simultaneously without causing the large-scale DNA damage that had been observed in earlier CRISPR-based experiments.

The achievement is particularly significant because previous attempts at editing human embryos often resulted in serious genetic disruptions, including chromosome loss and unintended mutations. Researchers say the latest results suggest base editing may offer a safer alternative.

Ethical Questions Return

The breakthrough has once again raised questions about how far gene-editing technology should be allowed to go. While scientists involved in the project emphasise that the goal is to prevent serious inherited diseases, critics warn that the same technology could eventually be used to select or enhance traits such as intelligence, height, appearance, or athletic ability.

The debate over human embryo editing intensified in 2018 when Chinese scientist He Jiankui claimed to have created genetically modified babies resistant to HIV. The experiment was widely condemned by the international scientific community, and He was later sentenced to prison by Chinese authorities.

Since then, many experts have argued that embryo editing remains too risky for clinical use due to concerns about safety, unintended mutations, and long-term health effects.

Potential Benefits for IVF Patients

Researchers believe the technology could eventually benefit couples undergoing IVF treatment. In some cases, embryos carrying disease-causing mutations are discarded because they are unsuitable for implantation. Gene editing may one day allow doctors to repair those mutations, increasing the number of viable embryos available to prospective parents.

Scientists involved in the study say future research will focus on reducing a problem known as mosaicism, where some cells within an embryo are edited while others remain unchanged. This remains one of the biggest barriers to clinical application.

Experts have also stressed that extensive testing, regulatory review, and public debate will be required before any human embryo gene-editing technology could be used in fertility clinics.

Sambhavna Seth to embrace motherhood via surrogacy after 7 IVF failures

Actor Sambhavna Seth and husband Avinash Dwivedi opt for surrogacy following years of physical and emotional struggle with unsuccessful IVF cycles.

Popular actor and digital creator Sambhavna Seth is set to embark on a new chapter of life as she prepares to become a mother through surrogacy. The news comes after the actor spent several years navigating the grueling process of In Vitro Fertilisation (IVF), characterized by multiple failures and a significant toll on her mental health.

Seth, who has consistently shared the highs and lows of her personal life through her YouTube vlogs, recently confirmed that she and her husband, Avinash Dwivedi, decided on surrogacy after seven unsuccessful IVF attempts. The couple’s journey has been one of resilience, marked by public scrutiny, personal health battles, and a steadfast commitment to their dream of parenthood.

Seven years of IVF struggles

The journey began shortly after the couple’s marriage in 2016. What followed was a decade-long cycle of hope and heartbreak. Seth has been vocal about the physical exhaustion that accompanies IVF, including intense hormonal treatments and the emotional vacuum created by repeated medical setbacks.

"Each failure felt like a personal loss," a source close to the family noted, reflecting on the actor’s previous public statements regarding her health. The repeated procedures reportedly led to bouts of depression and hormonal imbalances, challenges Seth chose to discuss openly to break the stigma surrounding infertility in the Indian entertainment industry.

Overcoming social media trolling

Being a public figure meant that Seth’s struggles were often played out in the digital spotlight. The actor frequently faced insensitive comments and trolling regarding her weight gain—a side effect of the hormonal medication—and her age.

Despite the negativity, Seth used her platform to address these issues head-on. She often called out the "insensitivity" of social media users, explaining that the changes in her body were a result of her fight to conceive. This transparency earned her a dedicated following of women who found solace in her honest portrayal of the difficulties associated with late-stage reproductive choices.

Support amidst family opposition

The couple’s path to this moment has never been traditional. Even before their fertility struggles, Sambhavna and Avinash faced significant hurdles, including initial opposition from their families regarding their marriage. Sources indicate that Seth’s parents were initially hesitant about the match, but the couple remained firm in their decision.

Throughout the failed IVF cycles, Avinash Dwivedi has been credited by Seth as her "anchor." While family pressure and societal expectations often peak during such times, the couple reportedly navigated these stresses by leaning on each other. Their bond, frequently showcased in their daily vlogs, has been a central theme in their transition toward surrogacy.

A shift toward surrogacy

The decision to opt for surrogacy marks a pivotal shift for the couple. In India, surrogacy laws have become more stringent in recent years, but it remains a viable path for couples facing proven medical infertility. For Seth, the move represents a pragmatic and hopeful end to years of invasive medical procedures.

By choosing to share this update, Seth joins a growing list of Indian celebrities who have opted for surrogacy to build their families, further normalizing the conversation around alternative reproductive methods in a country where traditional conception is often heavily romanticized.

From controversy to clarity

While Seth’s career has seen its fair share of reality TV drama and public spats—ranging from her volatile stint in the Bigg Boss house to social media controversies—this recent development shows a more grounded side of the performer.

Friends of the couple suggest that the focus has shifted entirely from the "noisy" world of showbiz to preparing for the arrival of their child. Local reports suggest the couple is currently busy with the necessary preparations, ensuring that this new journey remains as smooth as possible after years of turbulence.

Impact on the fan community

The announcement has triggered a wave of support across digital platforms. For many of her followers, Sambhavna’s story is not just about celebrity news but a mirror to the struggles faced by many urban couples. Her journey highlights the importance of mental health support during fertility treatments and the courage required to pivot when a particular medical path does not yield results.

As the couple moves forward, they continue to document their lives, albeit with a renewed sense of purpose and a long-awaited joy.